Hufflepie but now that I'm in the process of adding lighting using the URP/2D/Spine/Sprite shader, I'm running into an issue where the render texture ignores the normal map and light maps.

I'm not sure I understand your setup described in this sentence correctly. Do you want to apply lighting to the baked render texture (at the RenderQuad object where the skeleton was rendered to) instead of applying lighting to the skeleton before it is rendered to the render texture, then this is not an intended workflow of these example components. The render texture filled via these example components only contains the final baked color information. See this forum thread where this question was handled before. Or is there anything preventing you from applying the normal workflow of lighting the skeleton before it is rendered to the render texture?

@Hufflepie Thanks for the clarification. Upon checking the issue, I just discovered that when using the URP pipeline it indeed does not apply any lighting when executing the render to texture command buffer.

Unfortunately we don't know of a proper solution yet, as this seems to not be supported (or well obfuscated) by the Universal RP according to the following sources:
https://forum.unity.com/threads/camera-command-buffers-in-urp.1114219/
https://docs.unity3d.com/2022.1/Documentation/Manual/render-pipelines-feature-comparison.html
https://www.gamedev.net/forums/topic/708654-unity-commandbufferdrawmeshinstanced-does-not-work-with-urp/
https://forum.unity.com/threads/unity-commandbuffer-drawmeshinstanced-does-not-work-with-urp.1015129/

If anyone knows a solution on how to render to a RenderTexture using lit URP or URP 2D shaders, please share your insights here on the forum. Otherwise I'm afraid there is little we can do.

Thanks for your understanding. Happy to integrate a fix for this issue any time.