Which version of the spine-unity runtime are you using (the latest 3.8 or 4.0-beta runtime)?
Which version of Unity?
What are your settings at the SkeletonGraphic component, could you please show a screenshot of the Inspector, with the Advanced
section expanded? Do you have Advanced - Multiple Canvas Renderers
enabled?
In general please always provide as much context information up front as possible, or send us a minimal Unity project that still shows the problem (you can send it as a zip package to contact@esotericsoftware.com). Otherwise days will pass unnecessarily until you read and answer our request.
We have an issue ticket here which deals with this issue, or a very similar issue:
https://github.com/EsotericSoftware/spine-runtimes/issues/1875
Most likely it should be resolved when this ticket is done. Still, a reproduction Unity project would help us test for your issue more efficiently.